Publications - Eye-yon https://eye-yon.com/category/publications/ Eye-yon Mon, 24 Nov 2025 14:46:47 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.1 https://eye-yon.com/wp-content/uploads/2025/04/cropped-Artboard-–-72-32x32.png Publications - Eye-yon https://eye-yon.com/category/publications/ 32 32 EndoArt®: Redefining Corneal Edema Care https://eye-yon.com/endoart-redefining-corneal-edema-care/ Wed, 08 Oct 2025 08:54:42 +0000 https://eye-yon.com/?p=4767 EyeYon Medical was featured in The Ophthalmologist with a comprehensive article exploring seven clinical patient profiles that help guide the use of EndoArt® in the management of endothelial disorders. Through the experiences of leading European corneal surgeons – including Prof. Björn Bachmann, Prof. David Lockington, Prof. Peter Szurman, Prof. Alain Saad, Mr. Romesh Angunawela, Prof. […]

The post EndoArt®: Redefining Corneal Edema Care appeared first on Eye-yon.

]]> EyeYon Medical was featured in The Ophthalmologist with a comprehensive article exploring seven clinical patient profiles that help guide the use of EndoArt® in the management of endothelial disorders.

Through the experiences of leading European corneal surgeons – including Prof. Björn Bachmann, Prof. David Lockington, Prof. Peter Szurman, Prof. Alain Saad, Mr. Romesh Angunawela, Prof. Diane Bernheim, and Prof. Sorcha Ní Dhubhghaill – the publication highlights real-world cases that reflect the diversity of clinical scenarios where EndoArt® can provide meaningful outcomes.

These profiles illustrate how EndoArt® is being applied across complex indications – from regraft and tissue shortage cases to silicone oil eyes, ICE syndrome, and non-donor candidates – offering valuable guidance on patient selection and surgical decision-making in corneal edema care.

The post EndoArt®: Redefining Corneal Edema Care appeared first on Eye-yon.

]]> Corneal Artificial Endothelial Layer (EndoArt) in Outpatients: Outcomes From a Case Series https://eye-yon.com/corneal-artificial-endothelial-layer-endoart-in-outpatients-outcomes-from-a-case-series/ Mon, 24 Nov 2025 14:40:32 +0000 https://eye-yon.com/?p=4893 Abstract Purpose: The aim of this study was to describe the surgical approach and outcomes of artificial endothelial layer (EndoArt) implantation in chronic corneal edema. Methods: Fifteen eyes of 15 patients with chronic corneal edema were implanted with an artificial endothelial keratoprosthesis (EndoArt, EyeYon Medical, Israel) several months (range: 2–108 months; mean: 42.7 ± 38.5 […]

The post Corneal Artificial Endothelial Layer (EndoArt) in Outpatients: Outcomes From a Case Series appeared first on Eye-yon.

]]>

Abstract

Purpose:

The aim of this study was to describe the surgical approach and outcomes of artificial endothelial layer (EndoArt) implantation in chronic corneal edema.

Methods:

Fifteen eyes of 15 patients with chronic corneal edema were implanted with an artificial endothelial keratoprosthesis (EndoArt, EyeYon Medical, Israel) several months (range: 2–108 months; mean: 42.7 ± 38.5 months) after at least one Descemet membrane endothelial keratoplasty failure or as a first-line procedure to improve anterior segment visibility ahead of a second procedure (phaco + Descemet membrane endothelial keratoplasty) in outpatient procedures. A 20% SF6–air mixture was used as a tamponade to secure the EndoArt in place. The number of transfixing sutures (1–4) was based on surgeon judgment and preference, considering patient-specific anatomical factors such as aphakia or previous graft configuration. The original technique used only 1 suture. Measured outcomes included changes in central corneal thickness, best corrected visual acuity (logMAR), rebubbling rate, and postoperative complications.

Results:

The preoperative mean central corneal thickness (844 ± 236 µm) decreased significantly postoperatively in all patients (607 μm ± 251 μm at the last visit (1 to 6 months), reduction of 28%, P-value <0.05). Ten eyes (66.7%) required at least 1 rebubbling. Three eyes required more than 2 rebubblings. Eighty percent of patients (12/15) were pseudophakic at the time of surgery.

The mean best corrected visual acuity improved significantly from 2.13 ± 0.19 logMAR preoperatively to 1.84 ± 0.53 logMAR at the final follow-up (P-value <0.05). Postoperative complications included intraocular pressure elevation (33%), partial implant detachment (66.7%), 1 intraoperative posterior dislocation, and 1 case of retinal detachment.

Conclusions:

EndoArt may represent a therapeutic option for chronic corneal edema in complex cases where conventional endothelial keratoplasty has failed or carries a high risk of failure. It improves visual acuity and significantly reduces corneal thickness within 3 to 6 months of surgery.

 

Full Publication

The post Corneal Artificial Endothelial Layer (EndoArt) in Outpatients: Outcomes From a Case Series appeared first on Eye-yon.

]]> Long-Term Observations of the First Human Implantation of an Artificial Endothelial Layer for Endothelial Dysfunction: a Pilot Study https://eye-yon.com/long-term-observations-of-the-first-human-implantation-of-an-artificial-endothelial-layer-for-endothelial-dysfunction-a-pilot-study/ Tue, 19 Aug 2025 09:21:40 +0000 https://eye-yon.com/?p=4637 Up to 6-year follow-up shows significant corneal edema reduction, stable outcomes, and no serious implant-related complications after first human EndoArt® implantation

The post Long-Term Observations of the First Human Implantation of an Artificial Endothelial Layer for Endothelial Dysfunction: a Pilot Study appeared first on Eye-yon.

]]> Up to 6-year follow-up shows significant corneal edema reduction, stable outcomes, and no serious implant-related complications after first human EndoArt® implantation

The post Long-Term Observations of the First Human Implantation of an Artificial Endothelial Layer for Endothelial Dysfunction: a Pilot Study appeared first on Eye-yon.

]]> Long-Term Clinical Outcomes and Anterior Segment Optical Coherence Tomography Findings After Artificial Endothelial Replacement Membrane Implantation https://eye-yon.com/long-term-clinical-outcomes-and-anterior-segment-optical-coherence-tomography-findings-after-artificial-endothelial-replacement-membrane-implantation/ Wed, 04 Jun 2025 06:12:54 +0000 https://eye-yon.com/?p=3854 The study evaluates the long-term outcomes of the EndoArt artificial endothelial implant in patients with chronic corneal edema. Over two years, the device significantly improved visual acuity and reduced corneal thickness, with stable integration aided by fibrotic tissue formation at the implant edge

The post Long-Term Clinical Outcomes and Anterior Segment Optical Coherence Tomography Findings After Artificial Endothelial Replacement Membrane Implantation appeared first on Eye-yon.

]]> The study evaluates the long-term outcomes of the EndoArt artificial endothelial implant in patients with chronic corneal edema. Over two years, the device significantly improved visual acuity and reduced corneal thickness, with stable integration aided by fibrotic tissue formation at the implant edge

The post Long-Term Clinical Outcomes and Anterior Segment Optical Coherence Tomography Findings After Artificial Endothelial Replacement Membrane Implantation appeared first on Eye-yon.

]]> 4.5 Year Follow-Up with a Novel Corneal Endothelial Prosthesis https://eye-yon.com/4-5-year-follow-up-with-a-novel-corneal-endothelial-prosthesis/ Wed, 04 Jun 2025 06:31:23 +0000 https://eye-yon.com/?p=3856 This 4.5-year follow-up study of the EndoArt corneal endothelial prosthesis showed 90% long-term adherence, significant reduction in central corneal thickness, and visual improvement in 60% of cases. The implant demonstrated safety and stability, offering a viable solution for patients with high risk of graft failure or limited access to donor tissue

The post 4.5 Year Follow-Up with a Novel Corneal Endothelial Prosthesis appeared first on Eye-yon.

]]> This 4.5-year follow-up study of the EndoArt corneal endothelial prosthesis showed 90% long-term adherence, significant reduction in central corneal thickness, and visual improvement in 60% of cases. The implant demonstrated safety and stability, offering a viable solution for patients with high risk of graft failure or limited access to donor tissue

The post 4.5 Year Follow-Up with a Novel Corneal Endothelial Prosthesis appeared first on Eye-yon.

]]> Corneal Artificial Endothelial Layer (EndoArt): Literature Review and Our Experience https://eye-yon.com/corneal-artificial-endothelial-layer-endoart-literature-review-and-our-experience/ Wed, 04 Jun 2025 06:32:09 +0000 https://eye-yon.com/?p=3858 Detailed review and clinical insights into EndoArt use for chronic corneal oedema cases.

The post Corneal Artificial Endothelial Layer (EndoArt): Literature Review and Our Experience appeared first on Eye-yon.

]]> Detailed review and clinical insights into EndoArt use for chronic corneal oedema cases.

The post Corneal Artificial Endothelial Layer (EndoArt): Literature Review and Our Experience appeared first on Eye-yon.

]]> EndoArt® Ergebnisse bei Patienten mit GlaukomDrainage-Implantaten EndoArt® results in patients with glaucoma drainage implants https://eye-yon.com/endoart-ergebnisse-bei-patienten-mit-glaukomdrainage-implantaten-endoart-results-in-patients-with-glaucoma-drainage-implants/ Wed, 04 Jun 2025 06:33:26 +0000 https://eye-yon.com/?p=3861 Retrospective findings on EndoArt effectiveness in GDD patients with high transplant failure risk.

The post EndoArt® Ergebnisse bei Patienten mit GlaukomDrainage-Implantaten EndoArt® results in patients with glaucoma drainage implants appeared first on Eye-yon.

]]> Retrospective findings on EndoArt effectiveness in GDD patients with high transplant failure risk.

The post EndoArt® Ergebnisse bei Patienten mit GlaukomDrainage-Implantaten EndoArt® results in patients with glaucoma drainage implants appeared first on Eye-yon.

]]> Suture Pull-Through Technique for EndoArt Insertion in a Complex Case Scenario https://eye-yon.com/suture-pull-through-technique-for-endoart-insertion-in-a-complex-case-scenario/ Wed, 04 Jun 2025 06:34:08 +0000 https://eye-yon.com/?p=3863 Case demonstrating novel technique ensuring safe EndoArt placement in high-risk scenarios.

The post Suture Pull-Through Technique for EndoArt Insertion in a Complex Case Scenario appeared first on Eye-yon.

]]> Case demonstrating novel technique ensuring safe EndoArt placement in high-risk scenarios.

The post Suture Pull-Through Technique for EndoArt Insertion in a Complex Case Scenario appeared first on Eye-yon.

]]> Short-term clinical and confocal microscopy changes after synthetic endothelial replacement https://eye-yon.com/short-term-clinical-and-confocal-microscopy-changes-after-synthetic-endothelial-replacement/ Wed, 04 Jun 2025 06:35:22 +0000 https://eye-yon.com/?p=3866 Short-term improvement in corneal clarity and reduced edema after EndoArt implantation.

The post Short-term clinical and confocal microscopy changes after synthetic endothelial replacement appeared first on Eye-yon.

]]> Short-term improvement in corneal clarity and reduced edema after EndoArt implantation.

The post Short-term clinical and confocal microscopy changes after synthetic endothelial replacement appeared first on Eye-yon.

]]> Busin Glide-Assisted Pull-Through Insertion of Artificial Corneal Endothelium (EndoArt) https://eye-yon.com/busin-glide-assisted-pull-through-insertion-of-artificial-corneal-endothelium-endoart/ Wed, 04 Jun 2025 06:36:40 +0000 https://eye-yon.com/?p=3869 Alternative implantation method reducing complications in severe endothelial dysfunction cases.

The post Busin Glide-Assisted Pull-Through Insertion of Artificial Corneal Endothelium (EndoArt) appeared first on Eye-yon.

]]> Alternative implantation method reducing complications in severe endothelial dysfunction cases.

The post Busin Glide-Assisted Pull-Through Insertion of Artificial Corneal Endothelium (EndoArt) appeared first on Eye-yon.

]]>