Innovative Drug Depot for Enhanced Topical Bioavailability

Hyper-CL™ Therapeutic Soft Contact Lens is the market’s first ocular drug depot system in the form of a non-invasive, comfortable, and easy-to-use contact lens. Its unique design increases the contact time of topical drops on the cornea, improving treatment.

Hyper-CL™ is indicated for various corneal conditions as well as post-surgical conditions and is clinically proven to relieve corneal pathologies, significantly increasing the quality of life. Hyper-CL™ is CE-approved for continuous wear and is in the commercialization stage across Europe and Asia.

 

the benefits of Hyper CL™

Increases contact time with drugs

With its unique design, Hyper-CL™ contact lens increases the contact time of therapeutic eye drops. More medicated time means better and faster outcomes.

Applied like other contact lenses

Hyper-CL™ therapeutic lens is easy to wear, clean, and remove as any other contact lens

Shields the eye

Adding another layer of protection, Hyper-CL™ therapeutic lens protects the eye, acting as a buffer from the eyelid and allowing for better healing.

The Need

Administration of topical drops is a common challenge for all eye diseases, where less than 5% of the topical drops reaches the target area of treatment.

The Hyper-CL™ Therapeutic Soft Contact Lens is intended for short-term wear (up to 7 days) to promote corneal healing and relieve corneal pain by protecting the cornea during the treatment of acute or chronic pathologies such as corneal edema, corneal erosions, entropion, bullous keratopathy, and corneal dystrophies, as well as post-surgical conditions resulting from cataract extraction and corneal surgery.

To increase the therapeutic effect, use of the Hyper-CL™ Therapeutic Soft Contact Lens in conjunction with an ophthalmic solution is recommended. Hyper-CL™ Therapeutic Soft Contact Lenses can even provide optical correction during healing, if required.

How does it work?

Step 1

Eye drops are administered and fill the reservoir by flowing into the space created by the Hyper-CL™.

Step 2

The unique shape of the Hyper-CL™ lens captures and holds the therapeutic eye drops against the cornea, extending the contact time and thus their efficacy.

Step 3

The lens can remain in the eye up to 7 days before cleaning, then up to another 7 days, after which time it is removed.

Hyper CL™ Publications

Dr. Nir Erdinest et al.

Hyper-CL for Fuchs endothelial corneal dystrophy

full article

Dr. Ofer Daphna et al.

Hyper-CL for corneal Edema: Prospective, Multicenter, Randomized, Cross-over Study

full article

Prof. Lional Raj Daniel Ponniah et al.

Winter ASCRS 2021 BK ePoster: Winning 1st Place

full article

Prof. Lional Raj Daniel Ponniah et al.

Hyper-CL for Bacterial Keratitis: Randomized Control Trial Results

full article

Prof. Vito Romano et al.

Hyper-CL for Sjögren's syndrome

full article

Prof. Giuseppe Giannaccare et al.

Hyper-CL and Insulin Eye Drops for the Treatment of Recalcitrant Neurotrophic Keratopathy

full article

Hyper CL™ Around The World

Italy

Spain

Germany

United Kingdon

United States

Leading experts worldwide trust Hyper CL™

The proportion of patients achieving a significant improvement in CCT and BCVA was greater in the therapeutic Hyper-CL™ group. In addition, the therapeutic Hyper-CL™ group had a greater improvement in mean BCVA and mean CCT.
Prof. Irit Barequet, MD
Prof. Irit Barequet, MDSheba Medical Center, Israel
I was able to try the Hyper-CL™ in a patient with a corneal melt, significant corneal edema, and Serratia infectious keratitis. The result was dramatic. The patient had resolution within a week with complete resolution of the patient’s AC inflammation/hypopyon. The epithelium was completely healed, and the infiltrate was almost completely resolved. Usually, these are long courses that take an average of 2 weeks to resolve.
Prof. Francis Mah
Prof. Francis MahMD, San Diego, CA, USA
The concept of using a novel drug repository contact lens is effective in prolonging corneal antimicrobial availability and drug contact time over the lesion and has demonstrated faster corneal healing, which may affect the overall outcomes in bacterial keratitis. Using a drug depo contact lens, may reduce the regimen of antibiotics, decrease treatment burden on the medical staff, improve patient tolerance, and reduce toxicities.
Prof. Lional Raj
Prof. Lional RajMD, Tirunelveli, India
Excellent results for our first patient. Patient and I satisfied with outcome. His Visual acuity improved from 20/200- to 20/60+.
Dr. Moshe Mendelson
Dr. Moshe MendelsonSilicon Valley Eye Physicians
I used lens for bullous keratopathy with excellent result. Corneal condition improves and then visual acuity too. I am excited to use more.
Dr. Navneet Toshniwal
Dr. Navneet ToshniwalIndia
The Hyper-CL™ is like a parachute; without it, you won't jump from an airplane. You must treat patients for an Epithelial Healing indication with the Hyper-CL™ + Serum.
Prof. Thomas Neuhann
Prof. Thomas NeuhannGermany
The Hyper-CL™ is working very well. (Case Report submitted to the American Journal of Ophthalmology - AJO)
Prof. Vito Romano
Prof. Vito RomanoItaly
“I've been using the lens ...so far, it's very comfortable. The improvement to my vision is remarkable. You have saved me from a corneal transplant! ...this level of improvement is a godsend. I can’t thank you enough.”
Patient TestimonialItaly
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